2/2024 - Excited that our 3DPath paper is a featured article in Nature Protocols. This was a huge collaborative effort outlining all the little details that we have refined over the years for sample prep, imaging, data processing and quantitative quality control.
1/2024 - Dr. Liu has been elected as a Fellow of SPIE, the international society for optics and photonics, joining the 2024 Fellows class!
11/2023 - Dr. Liu has been elected as a Fellow of Optica (formerly the Optical Society of America), joining the 2024 Fellows class!
3/2023 - Happy to report that the 3D datasets (original prostate biopsy images, ITAS3D-generated gland segmentation masks) and clinical outcomes for Weisi's 2022 Cancer Research paper are now publicly available through NIH's The Cancer Imaging Archive (TCIA) - https://doi.org/10.7937/44MA-GX21
6/2022 - The Molecular Biophotonics Lab has been awarded an R01 grant from the NIH/NCI entitled: "Prostate cancer risk stratification via computational 3D pathology." This is a 5-year collaborative project with Dr. Anant Madabhushi at Case Western Reserve University (moving to Emory University this Summer).
5/2022 - Congratulations to Lindsey Barner for successfully defending her thesis...her next stop will be at Nanostring Technologies in Seattle!
5/2022 - Our latest paper on OTLS microscopy, led by Adam Glaser, made the cover of Nature Methods!
[PDF | "News and views" editorial in Nature Methods ]
5/2022 - Congratulations to Dominie Miyasato on joining the next class of MD students at Harvard Medical School! She will be pursuing the MD track of the Harvard-MIT Program in Health Sciences and Technology (HST), one of the top educational programs focused on translational medical science and engineering.
1/2022 - Kudos to Weisi Xie for publishing the first of hopefully many papers on computational 3D pathology from our lab. Open-access article in Cancer Research with various press items: [PDF | medRxiv preprint | UW press release | thePathologist | ASME profile | FOX13 news video].
7/2021 - The Molecular Biophotonics Lab has been awarded an R01 grant from the NIH/NIBIB entitled: "Instrumentation platform for 3D pathology with open-top light-sheet (OTLS) microscopy." This project will continue to refine our OTLS-based imaging technologies to transform diagnostic pathology.
6/2021 - Lightspeed Microscopy Inc., which was spun out of the Liu lab and co-founded by Drs. Liu, True, Glaser, and Reder, has raised a $4M Series-A financing round led by Dynamk Capital.
4/2021 - Congratulations to Susana Simmonds Bohorquez for being awarded an NSF Graduate Research Fellowship!
3/2021 - Congratulations to graduate student, Rob Serafin, for being awarded a TL1 Translational Research Training Fellowship from the UW Institute of Translational Health Sciences (ITHS)!
3/2021 - Excited for undergrad, Kaylene Pang, who has won the OMAD Scholar Athlete Award at UW ... our lab got a shout out at her soccer match!
Kaylene was recently featured as a Mary Gates research scholar https://expd.uw.edu/mge/scholar-profiles/kaylene-pang/
2/2021 - Excited to finally publish our vision for nondestructive 3D pathology for clinical decision support in Nature Biomedical Engineering! We discuss the optical, computational and translational challenges ahead. Grateful for help from co-authors Adam Glaser, Kaustav Bera, Nick Reder, Larry True, Kevin Eliceiri, and Anant Madabhushi. [PDF]
https://www.nature.com/articles/s41551-020-00681-x%20
11/2020 - We are recruiting postdocs and graduate students! More details here:
https://engineering.academickeys.com/job/49610sdy
6/2020 - The Molecular Biophotonics Lab has been awarded an R01 grant from the NIH/NCI entitled: "In vivo dual-axis confocal microscopy of 5-ALA-induced PpIX to guide low-grade glioma resections." This is a 5-year collaborative project with Dr. Nader Sanai at the Barrow Neurological Institute in Phoenix, AZ, and DRVision in Bellevue, WA.
4/2020 - Congratulations to Kevin Bishop for being awarded an NSF Graduate Research Fellowship!
6/2019 - Congratulations to Adam Glaser on being awarded a K99/R00 "Pathway to Independence" grant from the NCI, which will provide him with 1 - 2 years of mentored support followed by 3 years of R01-level funding when he obtains an independent faculty position! Adam's paper on a 2nd-generation OTLS microscope has also now been published in Nature Communications [PDF | Supplement and videos | PreLights commentary]
3/2019 - Congratulations to undergraduate researcher, Kaylene Pang, a sophomore in mechanical engineering, for being awarded a Mary Gates Research Scholarship!
1/2019 - Congratulations to Ye Chen for successfully defending her Ph.D. dissertation!
9/2018 - Congratulations to Nick Reder for winning the Shark Tank competition at WMIC2018 for LightSpeed Microscopy! [Press Release]
5/2018 - Postdoctoral position available:
The molecular biophotonics laboratory has an opening for a postdoctoral associate to develop technologies for high-resolution volumetric imaging of human core-needle biopsies in order to optimize the treatments of individual patients. This research involves the continued development of open-top light-sheet (OTLS) microscopes, along with thick-tissue immunolabeling and optical-clearing techniques to image biopsy specimens in toto. [Postdoc ad]
4/2018 - The Molecular Biophotonics Lab has been awarded a grant from the Department of Defense (Army) Prostate Cancer Research Program (PCRP) entitled "Nondestructive volumetric pathology of prostate biopsies for accurate prognostication and treatment stratification." This project is a collaboration between Dr. Liu (project PI), Dr. Larry True (partnering PI), Dr. Nick Reder (pathology), Dr. Adam Glaser (engineering), Dr. Josh Vaughan (chemistry), Dr. Daniela Witten (biostatistics), and Dr. Jonathan Wright (urology).
5/2018 - Congratulations to Soyoung Kang for defending her PhD. dissertation and for being awarded this year's UW College of Engineering Student Teacher Award!
4/2018 - Congratulations to Lindsey Barner for being awarded an NSF Graduate Research Fellowship!
5/2017 - Congratulations to co-first authors, Dr. Yu "Winston" Wang, and Dr. Nick Reder, as well as many other contributing authors on a paper that has been accepted for publication in Cancer Research. The paper, entitled "Raman-encoded molecular imaging (REMI) with topically applied SERS nanoparticles for intraoperative guidance of lumpectomy,” is the product of a collaboration between the Liu lab and pathologists at the UW medical center (Dr. Nick Reder and Professor Suzy Dintzis).
5/2017 - Congratulations to co-first authors, Dr. Adam Glaser and Dr. Nick Reder, as well as the rest of the co-authors on a paper that has been accepted for publication in Nature Biomedical Engineering. The paper, entitled "Light-sheet microscopy for slide-free nondestructive pathology of large human specimens,” is the product of a collaboration between the Liu lab and pathologists at the UW medical center (Dr. Nick Reder and Professor Larry True). [PDF | Supplement and videos | "Behind the paper" blog | UW press release | KOMO news video | UW360 video | "News and views" editorial in Nat Biomed Eng | Editor's choice in Sci Transl Med | Interview in thePathologist | Blog post by @NIHDirector Francis Collins]
From left to right: Jonathan Liu, Adam Glaser, Larry True, Nick Reder, and Ye Chen
3/2017 - Dr. Adam Glaser has been awarded an F32 NRSA postdoctoral fellowship (3 years) from the NIH/NCI. His project is entitled: "Light-sheet microscopy (LSM) for rapid wide-area imaging and pathology of bread-loafed prostate specimens."
3/2017 - The Molecular Biophotonics Lab has been awarded an R21 grant from the NIH/NCI entitled: "Kinetic modeling of multiplexed SERS nanoparticles for quantitative molecular phenotyping (QMP) of breast cancer." This project is a collaboration between the labs of Dr. Liu (project PI) and Dr. Ken Tichauer at the Illinois Institute of Technology (IIT) in Chicago.
1/2016 - Our recently published work to develop a miniature microscope for cancer detection and surgical guidance is covered in the media (including Fortune, Mic, Gizmodo, Wired UK):
http://fortune.com/2016/01/28/cancer-microscope-nih/
http://gizmodo.com/this-pen-sized-microscope-could-spot-cancer-in-your-doc-1755135759
http://www.wired.co.uk/news/archive/2016-01/27/pen-detect-cancer-miniature-microscope
10/2015 - Congratulations to Jingwen Xiao, a senior undergraduate in Bioengineering, for receiving a Washington Research Foundation Fellowship for her work in our lab to develop a widefield deconvolution microscope for rapid analysis of prostate specimens.
5/2015 - Congratulations to Steven Leigh for successfully defending his thesis and receiving his Ph.D.!
4/2015 - Congratulations to Soyoung Kang for receiving an outstanding presentation award for her talk at the OSA Optics in the Life Sciences conference in Vancouver this month!
12/2014 - Congratulations to Danni Wang for successfully defending her thesis and receiving her Ph.D.!
9/2014 - We have moved to the department of mechanical engineering at the University of Washington (Seattle) in 8/2014.
Final day of packing at Stony Brook before the movers arrive:
12/2013 - The Molecular Biophotonics Lab has bee awarded an R01 grant from the NIH/NCI entitled: "Intraoperative confocal microscopy for quantitative delineation of low-grade glioma margins." This project is a collaboration between the labs of Dr. Liu (project PI) and Neurosurgeon Dr. Nader Sanai at the Barrow Neurological Institute in Phoenix, AZ, which sees the largest volume of glioma patients in the nation.
4/2013 - Congratulations to high school intern, Nebiyou Getahun, who was selected as a finalist for the 2013 National BioGENEius challenge in Chicago. Neibyou is heading to Harvard University in the Fall.
4/2013 - Steven Leigh, Danni Wang, Ye Chen, and Madhura Som have all received travel scholarships for the Engineering Conference International (ECI): Advances in Optics for Biotechnology, Medicine and Surgery meeting at Lake Tahoe (6/2013).
1/2013 - Press release and video introducing our work on brain tumor resection:
1/2013 - The Molecular Biophotonics Lab has been awarded an R21 grant from the NIH/NIBIB entitled: "Endoscopic molecular imaging of esophageal cancer with multiplexed Raman nanoparticles."
9/2012 - Danni Wang's paper has been accepted for publication in Translational Oncology in its original form without revisions! This contribution has been chosen as the cover article.
8/2012 - The Molecular Biophotonics Lab has been awarded an R01 grant from the NIH/NIDCR entitled: "Line-scanned MEMS-based dual-axis confocal microscopy to detect oral lesions in vivo." This project is a collaboration between the labs of Dr. Liu (project PI) and Dr. Milind Rajadhyaksha at the Memorial Sloan Kettering Cancer Center in Manhattan.
5/2012 - Steven Leigh's paper has been accepted for publication in Optics Letters in its original form!
4/2012 - Ye Chen wins another summer scholarship from the Stony Brook University Undergraduate Research & Creative Arts (URECA) Program.
4/2012 - Congratulations to high school intern, Jack Zhou, who was selected as a semifinalist for the Intel Science Talent Search and the Siemens Competition in Science, Math, and Technology. Jack has also been accepted into Harvard and Yale.
7/2011 - Congratulations to Danni Wang and Steven Leigh for passing their Ph.D. qualifying exams! We have high hopes for these rising stars in our lab.
5/2011 - Congratulations to graduating seniors: Sunny Patel, Ryan Chowdhury, Jerin Jospeh, and Jordan Riviello for winning the 2011 CEAS Socially Responsible Engineering Design Award for their senior design project on "Portable Screening Microscopy." (mentored by Dr. Liu)
4/2011 - Congratulations to Ye Chen for being admitted into the 2011 Undergraduate Research & Creative Activites (URECA) Summer Research Program, which provides her with a 10-week summer stipend!
1/2011 - Research is featured in BioOptics World: "Miniature microscopes for guiding brain tumor resection," authored by Danni Wang (grad student), Steven Leigh (grad student), and Jonathan Liu